The Chemistry and Function of Proteins Second EditionPDF电子书下载
外文
- 作 者:
- 出 版 社:Academic Press Inc.
- 出版年份:1963
- ISBN:
- 页数:455 页
图书介绍: 查看图书目录点击购买PDF全本电子书 上一篇:TOOLS FOR MANPOWER PLANNING THE WORLD BANK MODELS VOLUME II下一篇:ENVIRONMENTAL POLITICS AND POLICY THIRD EDITION 《The Chemistry and Function of Proteins Second Edition》目录 标签:
Ⅰ.Role of Proteins in Biology1
References5
Ⅱ.Purification,Isolation,and Determination of Proteins6
A.Methods of Isolation and Separation from Nonprotein Material6
B.Fractionation of Protein Mixtures12
C.The Problem of Protein Heterogeneity15
D.Qualitative Tests for Proteins19
E.Quantitative Determination of Proteins20
References22
Ⅲ.The Amino Acid Composition or Proteins25
A.Cleavage by Hydrolysis and Other Methods25
B.Determination of Rate of Hydrolysis27
C.Fractionation and Isolation of Amino Acids29
D.Amino Acids:General Properties and Specific Reactions33
E.Quantitative Determination of Amino Acids in Proteins42
References48
Ⅳ.Amino Acid Sequence and Primary Structure or the Proteins51
A.General Technique51
B.Determination of the N-Terminal Amino Acids52
C.Determination of the C-Terminal Amino Acids55
D.Partial Degradation of Proteins and Separation of Peptides57
References60
Ⅴ.Size and Shape or Protein Molecules62
A.Introduction.The Molecular Weight of Proteins62
B.Osmotic Pressure of Proteins65
C.Diffusion Rate of Proteins68
D.Sedimentation Equilibrium70
E.Sedimentation Velocity of Proteins72
F.Viscosity of Protein Solutions76
G.Flow Birefringence79
H.Polarization of Fluorescence80
I.Light Scattering by Proteins81
J.Other Methods Used for the Determination of Molecular Weights and the Shape of Proteins in Their Solutions83
K.Electron Micrography of Dry Proteins83
L.X-Ray Analysis of Protein Crystals85
M.Comparison of Molecular Weights and Shapes Found by Different Methods86
References89
Ⅵ.Electrochemistry and Hydration or Proteins92
A.Amino Acids as Dipolar Ions92
B.Ionization of Proteins98
C.Electrophoresis of Proteins104
D.Hydration and the Specific Volume of Solutes111
E.Hydration of Dry Protein115
F.Hydration of Proteins in Solution118
G.Solubility of Proteins in Water121
H.The Dielectric Properties of Protein Solutions123
I.The Role of Proteins in Energy Transmission127
References129
Ⅶ.The Internal Structure of Globular Proteins132
A.General Considerations132
B.Examination of Globular Proteins by X-Ray Diffraction134
C.Refractivity and Absorbancy of Protein Solutions140
D.The Optical Rotation and Rotary Dispersion143
E.Cross-Links in Globular Proteins149
F.Chemical Reactivity of Proteins154
G.The Problem of Branched or Cyclic Peptide Chains159
H.Denaturation of Proteins161
I.Kinetics and Thermodynamics of Denaturation166
J.Proteins in Interfaces174
References178
Ⅷ.Albumins,Globulins,and Other Soluble Proteins184
A.Classification of Soluble Proteins184
B.Proteins of the Blood Serum184
C.Fibrinogen and Its Conversion to Fibrin193
D.Milk Proteins197
E.Egg Proteins199
F.Vegetable Proteins202
G.Protamines and Histones204
References207
Ⅸ.Structural Proteins(Scleroproteins and the Muscle Proteins)211
A.General Remarks211
B.Collagen and Gelatin212
C.Keratin217
D.Fibroin221
E.Other Scleroproteins222
F.Biological Importance of Structural Proteins223
G.Muscle Proteins(Contractile Proteins)224
References230
Ⅹ.Combination of Proteins with Other Substances234
A.Intermolecular Forces234
B.Combination of Proteins with Inorganic Ions237
C.Combination of Proteins with Organic Dyes231
D.Combination of Proteins with Other Organic Substances238
References243
Ⅺ.Conjugated Proteins245
A.Survey on Composition and Properties245
B.Lipoproteins246
C.Glycoproteins(Mucoproteins)250
D.Metalloproteins256
E.Hemoglobin:General Properties261
F.Hemoglobin:Combination with O2 and Other Ligands.Conformation264
G.The Specificity of Hemoglobins271
H.Other Chromoproteins277
I.Nucleoproteins279
References289
Ⅻ.Enzymes:Proteins with Enzymatic Properties296
A.The Function of Proteins as Enzymes and Apoenzymes296
B.The Active Site of Enzymes299
C.Specificity of Enzymes303
D.The Enzyme-Substrate Complex307
E.Kinetics of Enzyme Reactions310
F.Proteinases and Peptidases315
G.Other Nonoxidative Enzymes321
H.Enzymes Involved in Oxidoreduction327
References340
ⅩⅢ.Proteins with Hormone Action347
A.General Remarks347
B.Thyroglobulin and the Thyroid Hormones347
C.Insulin349
D.Oxytocin and Vasopressin352
E.The Melanocyte-Stimulating Hormone(MSH)or Intermedin354
F.Adrenocorticotropic Hormone(ACTH)or Corticotropin355
G.Other Hormones of the Anterior Pituitary Lobe356
H.Other Protein Hormones and Peptides with Hormone-like Action358
References360
ⅩⅣ.Toxins(Toxic Proteins)363
A.Bacterial Exotoxins363
B.Bacterial Endotoxins364
C.Cyclic Peptides365
D.Other Toxins366
References367
ⅩⅤ.Role of Proteins in Immunological Reactions369
A.Antigens369
B.Antibodies:Their Detection and Isolation374
C.Antigen-Antibody Interaction379
D.The Mechanism of Antibody Formation384
E.Complement389
References390
ⅩⅥ.Protein Biosynthesis394
A.Introduction394
B.Amino Acid Supply395
C.Nonenzymatic Formation of Peptide Bonds399
D.Formation of Peptide Bonds by Proteolytic Enzymes402
E.Activation of Amino Acids for Protein Biosynthesis405
F.Incorporation of Amino Acids into Ribonucleoprotein Particles409
G.The Sites and the Rate of Protein Biosynthesis411
H.The Problem of Peptide Intermediates416
I.The Role of DNA and Messenger RNA in Protein Biosynthesis419
J.The Action of Analogs,Mutagens,and Inducers421
K.Templates and the Coding Problem423
References440
INDEX445
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摘要:本文详细介绍了《The Chemistry and Function of Proteins Second Edition.pdf》电子书版文档的下载,从其内容概述、结构特点、应用领域和下载方法四个方面进行了深入剖析,旨在为读者提供全面了解该电子书的机会。
1、内容概述
《The Chemistry and Function of Proteins Second Edition.pdf》是一本专注于蛋白质化学和功能的权威著作。该书第一版自出版以来,受到了学术界和工业界的广泛认可。第二版在第一版的基础上进行了全面修订和更新,涵盖了蛋白质化学、结构、功能、疾病和药物等方面的最新研究成果。
全书共分为十二章,包括蛋白质的基本概念、氨基酸、蛋白质的结构、蛋白质的合成、蛋白质的功能、蛋白质与疾病的关系、蛋白质药物等。书中不仅介绍了蛋白质的基础知识,还结合实际案例,深入探讨了蛋白质在生物体中的重要作用。
此外,书中还介绍了蛋白质研究的新技术和新方法,如X射线晶体学、核磁共振、质谱等,为读者提供了丰富的实验数据和实例。
2、结构特点
《The Chemistry and Function of Proteins Second Edition.pdf》在结构上具有以下特点:
首先,全书结构严谨,逻辑清晰。从蛋白质的基本概念入手,逐步深入到蛋白质的结构、功能、疾病和药物等方面,使读者能够系统地了解蛋白质的相关知识。
其次,书中内容丰富,图文并茂。不仅介绍了蛋白质的基础知识,还结合实际案例,使读者能够更好地理解和掌握蛋白质的相关内容。
最后,书中注重理论与实践相结合。在介绍蛋白质的基础知识的同时,还介绍了蛋白质研究的新技术和新方法,使读者能够将所学知识应用于实际研究中。
3、应用领域
《The Chemistry and Function of Proteins Second Edition.pdf》在以下领域具有广泛的应用价值:
首先,在生物学领域,该书为研究蛋白质的结构、功能和疾病提供了重要的理论基础。
其次,在医学领域,该书有助于了解蛋白质与疾病的关系,为疾病的治疗和预防提供参考。
最后,在药物研发领域,该书为蛋白质药物的设计和开发提供了重要的指导。
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总结:
《The Chemistry and Function of Proteins Second Edition.pdf》是一本内容丰富、结构严谨、应用广泛的蛋白质化学和功能权威著作。通过本文的介绍,读者可以全面了解该电子书的内容、结构、应用领域和下载方法,为学习和研究蛋白质提供有力支持。
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